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A large study suggests loneliness and social isolation can cost people years of healthy life, especially when it comes to mental health. Men experiencing both lost about 5.8 years free from depression and anxiety, while women lost roughly 3.7 years.

A short course of immunotherapy before surgery may offer remarkably durable protection for some patients with stage two or three bowel cancer. In the NEOPRISM-CRC trial, 32 patients with a specific genetic form of bowel cancer received pembrolizumab ...

Chronic diabetic wounds may fail to heal because immune cells remain locked in damaging inflammatory states instead of transitioning toward tissue repair. Researchers are exploring treatments that reprogram these immune responses, raising hopes for . ...

Depression may not be one biological condition, but several distinct patterns of brain activity hiding under the same diagnosis. Researchers studying 263 people with depression identified five brain profiles, each showing different patterns of ...

A six-month study suggests that high-intensity interval training (HIIT) may offer older adults a powerful advantage: losing body fat while keeping their muscle. Unlike moderate-intensity workouts, which led to a small loss of lean muscle, HIIT ...

Researchers have uncovered a new way bacteria detect viral attacks: a virus-produced enzyme cuts a bacterial sensor protein, triggering a self-destructing immune response. The discovery could lead to more effective phage therapies against antibiotic ...

Nicotine e-cigarettes appear to help more smokers quit than patches, gum, and several other common approaches, according to a major review of 80 clinical trials. Researchers say regulated vaping products are not risk-free, but may be a significantly ...

Five natural compounds, including curcumin and berberine, were tested for their effects on cancer cells and healthy muscle cells. All disrupted cancer cell energy production and pushed many of the cells into a non-dividing state, with curcumin ...

Researchers at Yale have identified a promising new approach to osteoarthritis that could do more than simply ease pain. The epilepsy drug lacosamide appears to block a protein involved in both pain signaling and cartilage destruction, helping ...

Just seven strength-training sessions helped obese mice shrink visceral fat cells and reactivate molecular pathways involved in burning stored fat, despite no change in overall body weight. The findings suggest some benefits of resistance exercise .. ...