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Scientists have uncovered why two seemingly opposite ways of targeting the same brain receptor can both promote weight loss. In mice, activating the GIP receptor in the brainstem reduced appetite, while blocking it in the hypothalamus removed a kind ...

Scientists have discovered that the aging human brain may be far less isolated from the rest of the body than once believed. Stanford researchers found that large numbers of immune cells from the blood begin entering the brain as early as middle age, ...

Simply choosing the stairs could have surprisingly big benefits for your heart and longevity. A large analysis involving more than 480,000 people found that regular stair climbers were 39% less likely to die from cardiovascular disease and 24% less . ...

A surprising stress-related signal may help the brain repair itself after injury. Researchers found that myelin-producing precursor cells rapidly release the stress hormone CRH near damaged brain tissue, helping control how those cells mature and ...

Women who used estrogen-only hormone therapy later in life were less likely to develop dementia and showed fewer signs of Alzheimer's disease in their brains, according to a large study of more than 21,000 participants. Hormone therapy use was linked ...

A large study of more than 5,500 adults over 50 found a striking combination of risk factors: abdominal obesity paired with vitamin D deficiency was linked to a 123% higher risk of death over six years. Each condition was associated with increased .. ...

Researchers have discovered that a gene linked to congenital heart disease acts like an architect for the heart cell's DNA. Losing just one copy of TBX5 can cause the genome's carefully folded 3D structure to unravel, disrupting the genes needed to . ...

Orange juice may have a much bigger effect on the body than scientists once realized. Drinking it regularly appears to influence genes tied to inflammation, blood pressure, metabolism, and blood sugar control, while studies have also found ...

A protein inside appetite-controlling brain cells may play an important role in preventing overeating and obesity, particularly when high-fat foods are readily available. Unexpected differences between males and females could also help explain why .. ...

Researchers have found a striking new way to potentially eliminate HIV soon after infection using a one-time combination of three therapies. In newborn nonhuman primates treated within three days of exposure, the regimen--standard antiretroviral ...