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Researchers have uncovered a possible reason why the Alzheimer's risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. ...

Researchers have found a way to slash the processing time for 3D-printed zirconia crowns from as much as 100 hours to under 30 minutes. The advance could eventually let dentists print strong, customized permanent crowns for patients within a single . ...

Researchers have used AI to uncover the DNA signature of a key genetic "switch" involved in turning genes on. After analyzing about 500,000 DNA sequences, the model identified the initiator in roughly 60% of human genes. The breakthrough could help . ...

A decades-old compound may point to a new way of treating obesity by making the body burn more energy rather than simply reducing appetite. In mice, TOFA increased energy use by as much as 18%, reduced body fat without significant muscle loss, and .. ...

A massive analysis involving more than 100 million people has found strong links between recreational drug use and stroke, including among younger adults. Cocaine was associated with nearly double the risk of stroke, amphetamines with more than ...

Older adults with mild cognitive impairment and sleep problems who took at least 5,000 IU of vitamin D daily scored more than 13% higher on a cognitive test than those taking none. The preliminary findings suggest vitamin D could be worth studying as ...

Greenland sharks may live for 400 years without suffering the kind of retinal decline normally associated with aging. Researchers found healthy eye tissue and active proteins specially adapted for seeing blue light in the dim Arctic depths. DNA ...

Mice that developed compulsive drinking after alcohol abstinence showed more than double the activity in a brain region associated with stress and addiction. Because the signal appeared before they drank again, researchers think it could eventually . ...

Peppermint oil may have an unexpected benefit for people with mildly high blood pressure. Adults who took a small dose twice daily for 20 days saw their systolic blood pressure fall by an average of 8.5 mmHg, while a placebo group showed little ...

Exercise may not be a powerful weight-loss tool on its own, but it appears to play a much bigger role in preventing lost weight from returning. By preserving muscle, supporting metabolism, improving fat burning, and regulating appetite and blood ...