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The 49ers held on for a 23-17 victory over the Commanders on Monday Night Football, but there are several big-picture concerns.

The 49ers will try to reach 6-0 without Deebo Samuel against Washington. Inside the receiver committee, Mike Evans' status, and Christian Kirk's possible debut.

The 49ers are vying for the NFC's top spot, and one name stands out from the rest as someone who could help elevate the offense.

The San Francisco 49ers have every reason to be optimistic about improving to 6-0 on the season, tearing away in the NFC West after both the Seattle Seahawks an ...

The Colts are likely going to be aggressive sellers prior to the NFL trade deadline, and the 49ers would be wise to poach one of these three players.

The stars seem to be aligning for a reunion between the San Francisco 49ers and DeForest Buckner with the way the Indianapolis Colts are trending.

The 49ers don't play until Monday night, but it's safe to say that Week 6 has already gone according to plan.

While the 49ers clearly hope Raheem Morris will stay as defensive coordinator, the Robert Saleh experience from last season should make them wary.

The 49ers' loss of Dre Greenlaw will leave the defense thinner than they've been all season.

Nick Bosa is reportedly progressing from his injury, but the 49ers would be foolish to try to bring him back either of the next two weeks.