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A key engine burn Thursday evening is expected to put the astronauts on an irreversible path around the moon.

If all continues to go smoothly, the crew is scheduled to fly around the moon Monday.

After a string of denials for rare disease treatment candidates, the FDA last week greenlit a drug for Hunter syndrome, a progressive illness affecting about 500 Americans.

Harrison Schmitt, now 90, was on the Apollo 17 mission -- the last time humans traveled to the moon. "Every day, every hour, every minute, is a new experience," he said.

Dr. Harrison Schmitt, Apollo 17 astronaut and the last person to walk on the moon, speaks with NBC News' Aaron Gilchrist about his experience, moon rock samples, and the significance of the upcoming Artemis II mission for the next generation.

Four astronauts are blazing NASA's trail back to the moon. Their mission, scheduled to launch on Wednesday, could take them farther from Earth than any human has gone before.

The squeaking of sneakers on a basketball court is one of sports' most recognizable sounds. NBC News' Steven Romo examines a recent study exploring the science behind this noisy phenomenon.

Four astronauts are set to lift off Wednesday on a journey around the moon -- the first such mission in more than 50 years.

The heat dome set more than 1,500 temperature records across 11 states. Temperatures were 20 to 30 degrees above average in some places.

On Wednesday, four astronauts are scheduled to launch on a trip around the moon -- the first such mission in more than 50 years. Images show NASA's long road to this point.