PARM is a deep-learning model trained on data from massively parallel reporter assays to help predict promoter activity in different human cell types, design synthetic promoters and identify key features of regulatory promoter grammar.
Systemic flavivirus dissemination in mosquitoes following initial infection requires protein-protein interactions within extracellular vesicles, which enable infectious particles to be transported through haemolymph and confer species specificity.
Bacteria use diverse defence systems against phages, including a 164-residue prophage-encoded protein, Rip1, which senses conserved phage assembly rings to form membrane pores that block virion maturation and trigger premature host cell death.
Mouse models demonstrate that vagal sensory neurons transmit signals from lung adenocarcinoma to the brain, increasing sympathetic efferent activity in the tumour microenvironment and thereby creating a immunologically permissive environment for ...
Continual automated data collection was once possible only for the world's richest labs. Now, sensor systems are commonplace and can be accessed from an app.