The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.
A study using Arabidopsis shows that plants can monitor the integrity of their outer barriers by sensing gas diffusion, enabling them to initiate wound repair to prevent water loss and pathogen entry.
A CRISPR knock-in strategy that uses endogenous gene regulatory mechanisms can engineer 'armoured' CAR T cells that secrete proinflammatory cytokines directly within a tumour without causing toxicity, leading to prolonged survival in mice.
Two distantly related methanogens shift the methanogenic pathway under nickel limitation, suggesting that methanogens adapt to changing bioavailability of nickel by rerouting electron flow between two different pathways.
An unconventional machine learning-based inverse design framework enables the generation of ultrabroadband and band-selective thermal meta-emitters with complex 3D architectures and diverse material compositions.
A method based on boron-mediated assembly is described for the synthesis of tetrasubstituted alkenes, molecules with four substituents around the central C=C bond, with complete control over the double-bond geometry.
New evidence suggests that Neanderthals rendered fat from bones to stave off protein poisoning. Plus an interstellar object is about to pass through our Solar System and why some animal mimics aren't great replicas.
The publication of ever-larger numbers of problematic papers, including fake ones generated by artificial intelligence, represents an existential crisis for the established way of doing evidence synthesis. But with a new approach, AI might also save ...