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Tirzepatide, sold as Mounjaro and Zepbound, activated calorie-burning brown fat in obese mice, revealing a potential metabolic effect beyond appetite suppression. If confirmed in humans, the finding could help explain the drug's powerful benefits and ...

Scientists discovered a surprising energy paradox in the brain during REM sleep, the stage most closely associated with dreaming. Blood supply to the brain begins increasing even before REM starts, but neurons' immediately available energy, measured ...

Scientists discovered rare flavoalkaloids in Cannabis leaves for the first time, along with dozens of other phenolic compounds that had never been reported in the plant. The findings suggest that Cannabis leaves, often discarded as waste, may contain ...

A major analysis suggests Phelan-McDermid syndrome, a genetic disorder closely linked to autism, may affect about 1 in 7,300 people and more than 45,000 Americans. Researchers warn that thousands of cases may remain hidden because genetic testing is ...

Researchers used CRISPR to remove CD33 from donor stem cells, potentially giving doctors a way to attack aggressive blood cancers without destroying the healthy cells patients need after a transplant. In a 30-patient trial, the edited cells ...

A magnet-producing bacterium extended the average lifespan of C. elegans worms by more than 43% while helping protect their neurological and intestinal health. Researchers traced much of the effect to suppression of ferroptosis, a damaging form of .. ...

Scientists discovered a surprising backup system that lets mammalian cells make the essential amino acid cysteine even when the pathways once considered indispensable are disabled. The same survival mechanism may help cancer cells resist treatment, . ...

The brain may have a built-in way to quickly settle disagreements between regions processing the same scene. Researchers found that matching signals between two visual areas lasted longer, while conflicting signals rapidly faded away. This "consensus ...

A 70-year-old leukemia drug is still revealing new secrets. Researchers found that removing a protein called NUDT5 protected cells from the drug, even though simply blocking the protein had little effect. The unexpected result points to a hidden ...

A newly identified breakdown in communication between nerves and muscles could help explain why people lose strength as they age. Researchers were able to improve muscle strength in an animal model by targeting a key protein, raising hopes that some ...