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Researchers discovered a brain-based "brake" that can shut down chronic nerve pain in mice by calming an overactive pain circuit. Targeting this system more precisely could one day lead to powerful pain relief without affecting opioid receptors ...

Moderate calorie restriction lowered an immune protein called C3 that appears to help drive chronic inflammation as the body ages. Blocking the same protein reduced age related inflammation in mice, raising the possibility that future treatments ...

Britain's postwar sugar rationing created a rare natural experiment that let researchers examine how early sugar exposure might affect health decades later. People who experienced more rationing during their first 1,000 days had lower rates of ...

A compound found in turmeric may help protect blood vessels from some of the damage caused by Type 1 diabetes. In rats, curcumin reduced inflammation, improved cellular signaling, and restored vascular health to levels resembling those of nondiabetic ...

A wavelength of light largely missing from indoor LEDs may play an important role in protecting developing eyes from nearsightedness. Researchers found that indigo light completely prevented myopia in tree shrews, whose eyes share important ...

Early-life stress may physically alter how DNA is packaged in the brain, leaving stress-related genes primed to activate more easily years later. In mice, researchers were able to block this effect, preventing the heightened anxiety and stress ...

A low-carb diet may raise LDL cholesterol much more sharply in people who are genetically predisposed to high cholesterol, particularly when they consume lots of saturated fat. The findings could help explain why people following seemingly similar .. ...

A neuroscientist is challenging the idea that the brain contains a central system that actually "makes" our decisions. What we experience as choosing may instead emerge from the continuous interaction of perception, movement, the body, and the world ...

Older adults who received the Shingrix shingles vaccine were 24% less likely to be diagnosed with dementia over four years in a study of more than 500,000 people. Researchers estimate the difference could amount to roughly one dementia case prevented ...

Researchers have found a way to supercharge natural killer cells, powerful immune cells that can attack cancer, so they can penetrate solid tumors and keep fighting once inside. In mice, these specially prepared tissue-resident cells slowed the ...