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Combining a computational framework and optogenetic and chemogenetic manipulations within and downstream of the cortico-basal ganglia circuit identifies the specific cortico-basal ganglia synapses that drive the acquisition and expression of rapid .. ...

Reparative microglia persist in the brain after stroke but become dysfunctional through ZFP384-mediated mechanisms; however, this process can be mitigated by targeting Zfp384 using therapeutic antisense oligonucleotides.

Powerful quasar outflows could explain why many early galaxies stopped making stars.

A highly efficient navigation strategy taking inspiration from the visual learning flights of honeybees is described, which enables drones to quickly return from longer flights by means of path integration and uses a neural network as a view memory . ...

Treatment data for triple-negative breast cancer show the importance of macrophage subtypes and cancer-cell metaprograms for interferon signalling, HLA expression and cell cycle activity that are associated with a good response to neoadjuvant ...

A simple machine-learning algorithm, inspired by honeybees' visual memory and sense of direction, enables a flying robot to pinpoint its home location.

Pregnancy poses many challenges, including protecting against infection and increased nutritional demands. Pregnancy-associated gut changes offer some help.

Health outcomes were better in people who slept between about six and eight hours a day.

Electron-beam control enables deterministic placement of tens of thousands of atomic defects in three-dimensional crystals, creating stable, programmable artificial matter for scalable quantum and nanoscale technologies.

Antibiotics designed by artificial intelligence, immunotherapy for resistant infections and other highlights from studies and trials.