Iran's military said it fired missiles at a Jordanian air base used by American forces. Jordan said it had intercepted missiles entering its air space.
American officials said they were trying to safeguard maritime traffic in the Strait of Hormuz. Iran said it had responded by firing at U.S. bases in Qatar, Bahrain and Kuwait.
Tehran said it targeted Patriot missile interceptors in Kuwait, early warning systems in Qatar, and fuel depots in Bahrain, which is also the home of the US Navy's 5th Fleet.
The United States launched new airstrikes against Iran early Thursday, and Tehran responded by targeting U.S.-allied Mideast countries in an exchange of fire that threatened an interim deal intended to help end the war in the Middle East.
The U.S. military said it had hit dozens of Iranian targets for the second night in a row. Iran's military said it responded by firing missiles and drones at U.S. bases in Kuwait and Bahrain.