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Vanderbilt researchers created the first selective compound designed to inhibit TAOK-1, a poorly understood protein connected to Alzheimer's disease. They also discovered a second compound that activates the entire TAOK protein family, offering ...

Scientists have figured out how two famously poisonous plants create chemicals with surprising medical potential. After tracking thousands of genes in wolfsbane and larkspur, they identified six enzymes needed to build a complex compound called ...

A protein once thought to mainly protect chromosome ends may also be essential for keeping muscle stem cells ready to repair injuries. Researchers found that TRF2 helps these cells maintain their identity and coordinate the cycle of rest, repair, and ...

A surprisingly small dose of exercise may deliver major health benefits for adults carrying excess fat around the waist. In a four-month trial involving 315 adults with central obesity, researchers found that completing 75 minutes of brisk interval . ...

A sweeping review of more than 350 studies suggests that the protein boom may be overselling what many people actually need. Eating less protein appears to improve metabolism, reduce inflammation and cellular damage, and activate pathways linked to . ...

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes with small mistakes that allow new mutations to ...

A daily avocado may help lower heart disease risk in adults with obesity by reducing the number of LDL particles circulating in the blood. After six months, participants who ate an avocado each day experienced a decline associated with an estimated 4 ...

Scientists have identified an immune response that may explain why statins cause muscle pain, weakness, and exercise intolerance in some people. The finding could eventually lead to treatments that protect muscles while preserving the drugs' ...

Blood cancers that eventually worsen may carry detectable genetic warning signs years before patients develop serious symptoms. The findings could lead to earlier intervention while also helping doctors distinguish true cancer from harmless age ...

A new report suggests that blood pressure may be controlled more effectively by increasing potassium while also cutting sodium. Potassium-rich foods can help balance sodium's effects, but most people consume far less potassium than recommended.