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Spaceflight may dramatically change the gut within weeks, causing bacteria to break down more protein as food moves more slowly through the intestines. The shift could help explain astronaut constipation and may have wider effects on health, making . ...

A compound the body can make after eating pomegranates, walnuts, and some berries improved measures of heart function by up to 80% in animal models of a difficult-to-treat form of heart failure. Urolithin A helped stiff heart tissue relax and reduced ...

Scientists resurrected antimicrobial peptides from mammals that lived millions of years ago and found that some were more potent against drug-resistant bacteria than modern human versions. These evolutionary relics could provide new clues for ...

Strengthening the body's natural daily rhythms helped mice recover after stroke by improving the brain's waste-clearing system and reducing lingering inflammation. The approach worked even when treatment began three days after the stroke, suggesting ...

Scientists found that immune cells contributing to Alzheimer's-related brain damage may be activated in lymph nodes outside the brain before traveling into the nervous system. Blocking this pathway in mice dramatically reduced neurodegeneration and . ...

A large health-record analysis found that glucosamine use was associated with a 25% higher likelihood of mild cognitive impairment progressing to dementia. Lab experiments suggest the popular joint supplement may intensify an abnormal sugar-tagging . ...

Direct oral anticoagulants cut the risk of serious clinical events by 69% in atrial fibrillation patients with an intermediate risk of stroke, according to the randomized SINGLE-AF trial. The benefit was driven mainly by fewer ischemic strokes, with ...

A single dose of an experimental CRISPR therapy cut LDL cholesterol and triglycerides by about half in patients with difficult-to-treat lipid disorders. The reductions were still present one year later, with the highest dose lowering LDL by 52.5% and ...

Pain and fatigue in rheumatoid arthritis can persist even after inflammation improves, with depression, poor sleep, obesity, smoking, and chronic pain potentially helping sustain symptoms. Researchers say identifying these hidden drivers could ...

Scientists have mapped the genetics of cat cancer on an unprecedented scale and found surprising similarities with tumors in humans. The findings could help bring precision cancer treatments to cats while also revealing new clues about how human ...