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Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed higher levels of an enzyme that reduces a natural feel-good molecule in the brain. This imbalance .. ...

Researchers found that tau proteins don't jump straight into forming Alzheimer's-associated fibrils--first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This reveals a .. ...

Scientists identified a small molecule that interrupts a harmful protein pair linked to diabetic inflammation and tissue damage. The compound helped wounds heal faster and reduced organ stress in both Type 1 and Type 2 diabetes models. Unlike typical ...

By reactivating a long-lost gene, researchers were able to lower uric acid levels and stop damaging fat accumulation in human liver models. The breakthrough hints at a future where gout and several metabolic diseases could be prevented at the genetic ...

Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug candidate, the team was able to protect mitochondrial ...

Researchers have created a prediction method that comes startlingly close to real-world results. It works by aiming for strong alignment with actual values rather than simply reducing mistakes. Tests on medical and health data showed it often ...

Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens--and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers ...

Ultra-endurance athletes can push their bodies to extraordinary extremes, but even they run into a hard biological wall. Researchers tracked ultra-runners, cyclists, and triathletes over weeks and months, discovering that no matter how intense the .. ...

Researchers have uncovered surprising evidence that anxiety may be controlled not by neurons but by two dueling groups of immune cells inside the brain. These microglia act like biological pedals--one pushing anxiety forward and the other holding it ...

Scientists studying aging found that sensory inputs like touch and smell can cancel out the lifespan-boosting effects of dietary restriction by suppressing the key longevity gene fmo-2. When overactivated, the gene makes worms oddly indifferent to .. ...