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SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain while protecting joint tissue. Instead of blocking pain pathways, SN101 uses lab-grown nociceptors that . ...

Researchers discovered that tanning beds cause widespread, mutation-laden DNA damage across almost all skin, explaining the sharply increased melanoma risk. Single-cell genomic analysis revealed dangerous mutations even in sun-protected regions. ...

The study reveals how Balanophora plants function despite abandoning photosynthesis and, in some species, sexual reproduction. Their plastid genomes shrank dramatically in a shared ancestor, yet the plastids remain vital. Asexual reproduction appears ...

Scientists are uncovering a new possibility behind long COVID's stubborn symptoms: hidden infections that awaken or emerge alongside SARS-CoV-2. Evidence is mounting that viruses like Epstein-Barr and even latent tuberculosis may flare up when COVID ...

Scientists found that certain molecules made by gut bacteria travel to the liver and help control how the body uses energy. These molecules change depending on diet, genetics, and shifts in the microbiome. Some even improved insulin response in liver ...

A series of century-scale droughts may have quietly reshaped one of the world's earliest urban civilizations. New climate reconstructions show that the Indus Valley Civilization endured repeated long dry periods that gradually pushed its people ...

Male bonobos have an impressive ability to detect when females are most fertile, even though the usual visual cues are unreliable. Researchers tracking wild bonobos in the Congo discovered that males skillfully interpret a mix of swelling timing and ...

Senescent "zombie" cells are linked to aging and multiple diseases, but spotting them in living tissue has been notoriously difficult. Researchers at Mayo Clinic have now taken an inventive leap by using aptamers--tiny, shape-shifting DNA molecules- ...

Forskolin, a plant-derived compound, shows surprising potential against one of the most aggressive forms of leukemia. Researchers discovered that it not only stops cancer cells from growing but also makes them far more vulnerable to chemotherapy by . ...

Researchers used a deep learning AI model to uncover the first imaging-based biomarker of chronic stress by measuring adrenal gland volume on routine CT scans. This new metric, the Adrenal Volume Index, correlates strongly with cortisol levels, ...