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The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some surgeries and kidney stone pain, opioids performed no ...

Astronomers have spent years searching for a possible hidden giant planet far beyond Neptune. Unusual orbits among distant Kuiper Belt objects have fueled the Planet Nine theory, but recent discoveries are challenging the idea by showing more stable ...

NASA says a long-running air leak aboard the ISS recently worsened, leading engineers to investigate new suspected crack locations and consider a riskier repair strategy. Astronauts were temporarily moved into a safe haven as a precaution before the ...

Researchers have identified a new Alzheimer's target and created an experimental compound that blocks a damaging process inside brain cells. In mice, the treatment slowed nerve cell loss, reduced Alzheimer's-related changes, and even appeared to ...

Scientists have uncovered a key brain signal that helps us break old habits and adapt when circumstances suddenly change. By watching mice navigate a virtual maze, researchers found that disappointment--when an expected reward failed to appear- ...

What if our biggest idea about reality is built on a hidden misunderstanding? A new philosophical look at space-time challenges the popular view that the past, present, and future all exist together in a timeless "block universe." The argument ...

Scientists used nanoscale gold metamaterials to supercharge heat transfer across tiny gaps, achieving up to four times more energy flow than similar conventional systems. The breakthrough could lead to better chip cooling, more efficient energy ...

Ancient grooves on human teeth, once hailed as evidence of tooth-picking, may simply be the result of natural wear, according to a new study of wild primates. The research also revealed that a common modern dental defect appears to be uniquely human, ...

Researchers have solved a decades-old mystery by showing that a cache of 43 helmets found off the Spanish coast is medieval, not Roman. The remarkable discovery exposes a thriving weapons trade network that connected Mediterranean powers during a ...

South Australia's koala population has grown so large that it may be heading toward a self-made disaster, with forests struggling to support the animals. Researchers say targeted fertility control could prevent widespread starvation and habitat ...