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The dorsomedial prefrontal cortex encodes the value, salience and valence of learned stimuli along distinct neural dimensions, and the geometry of these representations shapes motivated behaviours in mice.

New hominin fossils from the Grotte à Hominidés at Thomas Quarry I (ThI-GH) in Casablanca, Morocco, dated to around 773 thousand years ago are similar in age to Homo antecessor, yet are morphologically distinct.

Researchers identify the neurons involved in the emotional distress associated with pain, and design a genetic approach that could soothe suffering without opioid drugs.

Human genetic variation influences instability of DNA repeats that commonly expand as we age.

Lipid transfer proteins (LTPs) maintain the specialized lipid compositions of organellar membranes1,2. In humans, many LTPs are implicated in diseases3, but for the majority, the cargo and auxiliary lipids facilitating transfer remain unknown. We ...

The existing ENCODE registry of candidate human and mouse cis-regulatory elements is expanded with the addition of new ENCODE data, integrating new functional data as well as new cell and tissue types.

Low levels of albumin, a protein found in blood, are associated with poor clinical outcomes for people with the fungal disease mucormycosis.

Albumin selectively inhibits Mucorales growth through the release of bound free fatty acids.

A new architecture based on high-valence sulfur/sulfur tetrachloride cathode chemistry is described for manufacturing high-voltage anode-free sodium-sulfur batteries, demonstrating promise for applications in grid energy storage and wearable ...

An observation-based storm-track proxy shows that the winter North Pacific storm track has shifted substantially polewards, suggesting regional impacts on precipitation and warming patterns, with implications for temperature variability and extreme . ...