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With its win last week, Wake Forest is now a factor in the ACC title chase, but Stanford could put an end to that fast. Here's the CFN preview and prediction.

Both West Virginia and Iowa State lost their Big 12 openers, and now it's a win-or-else situation for each team. Here's the CFN preview and prediction.

UCF got a big win to open the Big 12 season, and now it faces a Houston team looking for its first conference win. Here's the CFN preview and prediction.

After a tough start to the SEC season, South Carolina had better beat Kentucky or the heat will be turned up fast. Here's the CFN preview and prediction.

SMU has a favorable schedule ahead, but it has to get by a dangerous Boston College team that needs an ACC win. Here's the CFN preview and prediction.

Week 5 has its share of great games, including Alabama at Mississippi State, Washington at USC, and Florida at Missouri as part of the ten best picks against the spread.

Nebraska is unbeaten, but has anyone noticed? They look to keep rolling against a Maryland team in need of something positive. Here's the CFN preview and prediction.

It's been a rough start for both Purdue and Illinois, but the winner will finally be able to exhale. Here's the CFN preview and prediction.

Florida State needs a big win fast, but Virginia has a shot to make its own statement in the ACC race. Here's the CFN preview and prediction.

Indiana keeps on winning, but it hasn't been a dominant national title force yet. Rutgers will try to make this a game. Here's the CFN preview and prediction.