Media mogul Oprah Winfrey, 71, has revealed in a new interview the unexpected effects she experienced after going on blockbuster weight loss drugs to maintain her weight.
Celebrities have embraced GLP-1 medications for dramatic weight loss in 2025. Oprah Winfrey, Amy Schumer, Meghan Trainor and Lizzo share their health journeys.
"I've seen all of my relationships improve because the energy and presence and vitality and clarity that I bring to them is so different," Winfrey said.
Oprah Winfrey is opening up about the unwavering support she has received from partner Stedman Graham as she reflects on decades of living with obesity.
Oprah Winfrey reveals her transformation in new book "Enough," sharing how GLP-1 medication helped her overcome lifelong obesity struggles and food obsession.
Oprah Winfrey says the disappearance of so-called food noise is one of the most amazing effects of her GLP-1 drug. Plus now she can take or leave alcohol too.
Oprah Winfrey detailed that in addition to weight loss and renewed energy, her use of GLP-1 medications for weight loss also led her to stop drinking alcohol.