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The San Francisco 49ers released their latest injury updates headed into the team's Week 13 matchup vs. the Buffalo Bills.

The San Francisco 49ers announced they have signed OL Sebastian Gutierrez to the team's practice squad and released OL Cameron Erving.

The San Francisco 49ers 2024 Salute to Service nominee, George Kittle, enthusiastically cheered on his high school teammate during a Week 12 military flyover at Lambeau Field.

A step-by-step guide to creating Levi's Stadium executive chef Alvin Kabiling's turkey pot pie featured in "Tailgate Treats" presented by Safeway.

The San Francisco 49ers have opened the practice window for linebacker Dre Greenlaw from the Reserve/Physically Unable to Perform list.

Broadcast and streaming information for the San Francisco 49ers Week 13 matchup against the Buffalo Bills at Highmark Stadium on December 1, 2024.

The San Francisco 49ers announced they have signed OL Cameron Erving to the team's practice squad.

Catch up on the latest San Francisco 49ers headlines, powered by Cisco.

In the San Francisco 49ers Week 14 contest against the Chicago Bears, the team will wear their customized cleats on the field to amplify the causes close to their hearts off the field.

San Francisco 49ers quarterback Brock Purdy is the latest star to receive a positive "PupTalk" from the characters of Nickelodeon's PAW Patrol.