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Updated inactives and analysis based on the latest reports and official announcements leading up to kickoff.

This week, Mike Reiss highlights stats to know, rookie returners and where the lineman had dinner this week.

Looking to win the fourth game he has appeared in this season, San Francisco 49ers quarterback Mac Jones, listed as questionable for Sunday due to an oblique injury, is expected to play against the Tampa Bay Buccaneers, sources told ESPN's Adam ...

Arizona Cardinals QB Kyler Murray is expected to miss Sunday's game against the Colts due to a foot injury. Jacoby Brissett is slated to start.

All-Pro wideout Ja'Marr Chase is expected to play on Sunday against the Green Bay Packers, a source confirmed to ESPN's Jeremy Fowler.

Sources expect more trade activity ahead of this year's NFL trade deadline.

Our experts dive into the lines and player props that offer value for Week 6 and share their tips and bets.

Falcons No. 2 wide receiver Darnell Mooney has been ruled out for "Monday Night Football" against the Bills because of a hamstring injury.

The Bears will debut a new left tackle Sunday against the Commanders, starting Theo Benedet in place of Braxton Jones, coach Ben Johnson announced on Saturday.

The Bills placed S Damar Hamlin and DT T.J. Sanders on injured reserve and ruled LB Matt Milano out for Monday night's matchup against the Falcons, coach Sean McDermott announced Saturday.