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Take a look at players who have been ruled out for the San Francisco 49ers Week 1 matchup versus the Seattle Seahawks.

San Francisco 49ers News: The official source of the latest 49ers headlines, news, roster transactions, featured series, and more.

The San Francisco 49ers released their latest injury updates headed into the 2025 season opener versus the Seattle Seahawks.

Broadcast and streaming information for the San Francisco 49ers Week 1 matchup against the Seattle Seahawks at Lumen Field.

San Francisco 49ers team reporter Briana Jeannel addresses fans' biggest questions ahead of Week 1 vs. the Seattle Seahawks.

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Emirates American Football League and Emirates Flag Football League become the first UAE flag football operators to join forces with the 49ers ...

The San Francisco 49ers announced their eight season-long captains ahead of the team's Week 1 matchup vs. the Seattle Seahawks.

The 49ers have promoted WR Marquez Valdes-Scantling to the active roster and signed WR Russell Gage Jr. to the team's practice squad.